Rural counties have seen a disproportionate jump in deaths from prescription-drug overdoses in the past 15 years, increasing at a pace three times that of the nation’s most urban counties.

About three-quarters of all U.S. deaths caused by prescription drugs in 2014 were from opioid pain killers, making prescriptions a major part of the nation’s opioid epidemic.
Rural – or “noncore” – counties saw an average increase in prescription drug deaths rates of about 9 percent per year from 1999 to 2014. Central counties of large metropolitan areas (1 million residents or more), on the other hand, saw the death rate climb by less than 3 percent per year on average over the same period.
Rural counties started with lower prescription-drug death rates than cities, so smaller increases in raw numbers of deaths in rural places can mean a sharper growth in the death rate. But by the end of the study period, rural counties’ prescription-drug death rates equaled or exceeded the rates in metropolitan areas.
An analysis of Centers for Disease Control age-adjusted mortality data shows that, in general terms, the more rural a county, the greater the increase in its prescription drug-overdose death rate from 1999 to 2014. The exception to the rule is counties on the fringes of the nation’s largest metropolitan counties – metros with 1 million residents or more. There, in the suburbs of large cities, the death-rate didn’t climb as fast compared to the overall trend. (The dip in the trend in the chart, below, from left to right tells the story.)

Prescription medication accounts for about half of all drug deaths in the U.S., according to the Department of Health and Human Services.
Data like this are behind recent efforts of U.S. Agriculture Secretary Tom Vilsack to call attention to what he and officials at the Health and Human Services Department call an opioid epidemic in rural America.
“From 1993 until 2013, we have seen a 400 percent increase in opioid prescriptions,” Vilsack said in an appearance in Missouri last month. “We now have over 259 million prescriptions being filled on an annual basis. That is one for virtually every adult in the United States of America.”
Vilsack is head of an interagency project to raise awareness of opioid abuse. He has made appearances in Virginia, New Hampshire, Missouri, and other states since the initiative launched in June. USDA has awarded grants to develop telemedicine addiction treatment programs for rural areas.
The analysis of prescription drug-abuse death rates comes from a research team at DrugAbuse.com, a for-profit drug education and research organization that also connects drug abusers with treatment facilities.
The analysis found that the prescription drug-overdose death rate was highest for the middle-aged – 45 to 54 year olds. It also showed that six of the top 10 counties with the highest rate of prescription drug deaths were in West Virginia. Ten of the top 30 were in Kentucky.
